Science Ethics

wei_loon5063

Artificial liver 'could be grown'

The team previously grew a human ear on a mouse


The scientist who grew a human ear on the back of a mouse has suggested it may one day be possible to "grow" a liver. US researchers say the prospect of artificial livers has been brought closer because they have worked out how to grow deep networks of blood vessels - which has not been done before. The potential new source of livers for transplants was welcomed by campaigners as a way of closing the gap between the number of organs needed and those available. In the UK, there are only around 100 people waiting for a liver transplant, but the British Liver Trust said many people died before they reached the list. However experts have warned the laboratory-based research is a long way from working livers. Copying In 1997 Dr Jay Vacanti grew a human ear from cartilage cells the back of a mouse, causing outrage among animal rights and pro-life groups.

If we can't sort this problem out, we could be stuck with lab-based solutions we can't use

Larry Hench, Imperial College, London

Now Dr Vacanti, a transplant surgeon at Massachusetts General Hospital in Boston and Jeffrey Borenstein, micro-engineering expert at the nearby Draper Lab are looking at growing more complex tissues. Scientists had believed it was not possible to grow anything more complex than simple tissues, such as thin sections of knee cartilage and skin because of problems growing the blood vessel networks. To do this, they use a "frame" made of a biodegradable plastic. This is immersed in a solution of the patient's cells, then in a nutrient solution. As the cells multiply and link together, the frame dissolves, leaving a piece of cartilage which survives because oxygen and nutrients from surrounding fluids feed into the cells. But in thicker tissues, the nutrients are unable to get past the first few cell layers and need an internal blood supply to survive. The technique developed by the researchers involves copying the blood vessel network of a real liver and using 3D computer modelling and machining to mimic its construction. To copy the structure, they injected a liquid plastic into the blood vessels of a liver, wait for it to solidify and dissolve the liver tissue, leaving a solid cast of the organ's blood vessels. They can then take "measure up" and feed data into a computer to create a 3D model of a liver's blood supply. 3D This model is then "sliced up" on the computer into horizontal layers, which can be used to make a silicon mould. Biodegradable plastic is then poured into the mould to make enough slices that can be sandwiched together using pressure and heat, to create a scaffold for a whole liver. The scaffold then has to be injected with at least seven types of cells that make up the solid part of the liver. A solution of endothelial cells, which normally line blood vessels, then has to be pumped into the empty channels in the frame where they stick to the walls. These can then be grown in a nutrient to form a network of blood vessels within the scaffold which again dissolves over a few months. If each step of this process works, it would result in a functioning liver. But blood vessel networks grown this way have so far been tested in rats, with no leakage or obstruction of the blood flow. Linda Griffith, a tissue engineer at MIT, said one of the main problems of the idea would be getting all the right cell types to grow in the right places. She told New Scientist magazine, which sets out the research: "In just a gram of liver, you have around 100 million cells and it'd be very hard to position each and every one. Larry Hench, a tissue engineer at Imperial College, London added: "Currently, there's no way of keeping these implants sterile, and no one is really looking at that." "If we can't sort this problem out, we could be stuck with lab-based solutions we can't use." Nigel Hughes, chief executive of the British Liver Trust, told BBC News Online: "We know that the demand for livers is going to outstrip supply. "We hope to see all of this biotech science come to fruition."


http://news.bbc.co.uk/1/hi/health/1949073.stm


where is the human ethics in science???
human rights are being fought.. what people who fought for animal rights are deem as activist.....

is the result more important than life??  

i am wondering.... is there any secret lab in world where they conduct human experiment??

aku_EnSeM

poor that mouse...

scientists have to know the true meaning of science, every thing in this world are special...

Sephiroth

While I don't condone cruelty onto animals, sometimes sacrifices must be made to get the better result.

I just hope the animals don't suffer and the scientists don't play with them and do their jobs seriously.

aku_EnSeM

Originally posted by Sephiroth at 13-4-2007 09:17 AM
While I don't condone cruelty onto animals, sometimes sacrifices must be made to get the better result.

I just hope the animals don't suffer and the scientists don't play with them and do the ...

okay, and please kill that mouse right after their observation has been done.

wei_loon5063

While I don't condone cruelty onto animals, sometimes sacrifices must be made to get the better result.
definately not acceptable.............................   what sacrifice???? i`ve read this the ecomonist magazine once....
they uncover a dreaful and inhuman conspiracy........ killing of new born baby for their bone marrow for manufacturing of beauty product
baby bone marrow = someone to look prettier...........
does the two really  weigh equally??? is this the sacrifice that is ok to you?
animal or human........ the act is simply not ethical.........
i think the professional bodies ought looking into ethics in fresh graduates
be it science or engineering or lawyer or doctor.....
talk about doctor....... i despise those doctor who refuse to treat patient without prior payment......
what is the first job that a doctor should do???



I just hope the animals don't suffer and the scientists don't play with them and do their jobs seriously.
acceptable

me_ai

being a human mean that u should preserve what is around u...
icluding ur self, ur human frens, ur pets or other animals, ur environment...

all engineers, doctors , lawyer, anybody...
use ur knowledge as it should bring preserve and not to destroy...
we are human, do not act as u are god as u would never become god,

wei_loon5063

Originally posted by me_ai at 13-4-2007 06:39 PM
we are human, do not act as u are god as u would never become god

have you watch doraemon before???

there was this episode.... where nobita was brought to future.... in future there is this mythical zoo.....

where biotech was use to its limtis....

human are creating beast, creatures that was deem as a myth or legends

beast like griffin, unicorn, pegasus, cyclops..... etc......

human are tempting to be god in creating superbeing..........

aku_EnSeM

do you want to see your ass turns into an earlobe tomorrow????? :@ :@

me_ai

there are other movies or cartoons such as;
alone in the dark, ultraman (so many version of ultraman...latest is nexus sunday morning 10am)
shows that all those creature are threatening the human being....

trying to be super being, would only create chaos as those human will try manipulate anything...
as well...human genetic...
creating clone...increasing in population...
as there is no noble person in this world...probably all those technologies will be used for
killing other people...

wei_loon5063

Attack of the Clones???   :cak:

tau tak??

me_ai

yep tu satu hal...

satu lagi...planet bumi mana muat nak dok ramai2 dgn klon lak tu...
jalan selangkah tgk mamat sama muka pulak...

perompak bank kuar kat tv pun...muka sama....
adess sakit kepala

Sephiroth

by wei_loon5063

definately not acceptable.............................   what sacrifice???? i`ve read this the ecomonist magazine once....
they uncover a dreaful and inhuman conspiracy........ killing of new born baby for their bone marrow for manufacturing of beauty product

First of all, what are you talking about?

I'm talking about Science and sacrifice they have to make with rats and animals in order to experiment with it. You are talking about Human Experiments which has nothing to do with this.

Also, if you are so angry at humans been killed, go and find out how many abortions in how many countries have been conducted now. Also, go and research about Stem Cells and how Scientists are thinking of killing unborn feotus so they could harvest Stem Cells.

animal or human........ the act is simply not ethical.........

What is the difference between a Scientists who kills animals for experiments and people like you who kills animals for food? ;)

What is the difference between Scientists who kills animals for Science and people like you who sit at any "longkang" or "parit" which they can find and cast fishing rods to catch fish - ALL IN NAME OF FUN AND RELAXATION?

what is the first job that a doctor should do???
Scientists are NOT doctors. Scientists do not make any vows to save any lives. :no:

wei_loon5063

What is the difference between a Scientists who kills animals for experiments and people like you who kills animals for food?
survival........ and changing destiny........ a guy suppose to die cos of car crash.... then he was rescued by doctor..
the knowledge the doctor obtain are from animal experimants......
many animals = life of a human
rasionally..... IT do not equal.....
personally... it equals....
if the someone is someone that I care  

Scientists are NOT doctors. Scientists do not make any vows to save any lives.
i know.... whythey create medicine then??
remember.. Dr  do not know chemistry  

Atomic_Omnikid

http://www.technologyreview.com/Biotech/18988/

now human not only can create artificial earlobe,but can change the species of some microbes and create other artificial organs too..

In the future you can go to any bio labs and order 'tangan kiri satu'...

http://www.technologyreview.com/Biotech/18476/

..another usage of microbes to create alternative biofuels,thousands of microbes will die just to give our car fuel..

if human is truly wan create organism that really useful,they should create something that really opposite them...

wei_loon5063

Originally posted by Atomic_Omnikid at 3-7-2007 11:51 PM
http://www.technologyreview.com/Biotech/18988/

now human not only can create artificial earlobe,but can change the species of some microbes and create other artificial organs too..

In the f ...

this is only the initial goodies for us to support them

the ultimate goal is to clone soldiers

Atomic_Omnikid

Originally posted by wei_loon5063 at 4-7-2007 00:12


this is only the initial goodies for us to support them

the ultimate goal is to clone soldiers

soldiers?

why they want war in the first place...zzzzz...

wei_loon5063

Originally posted by Atomic_Omnikid at 4-7-2007 04:02 PM


soldiers?

why they want war in the first place...zzzzz...

POwer... domination....from greed....

All people have greed they want it ALL.... but they cant have it all...

there is a saying in chinese... one moutain cant sustain two tiger..... guess you get the meaning...

that is why we have war